The recognizable proof of coding successions in various species, incorporating human sooner rather than later, has introduced the post-genome period. In this time, advancements are getting to be accessible that permit the profiling of tissues and cell populaces at the genomic, transcriptomic and proteomic levels. The atomic investigation of tissues at all three levels has been alluded to as operomics. This audit covers some essential innovations for operomics and their application to some lymphoid issue. It is suggested that nobody sort of investigation is completely instructive and that data that can be gotten from the diverse compartments enveloped in operomics is complimentary. Prospects for bringing such profiling advances into the clinical research facility will rely upon their strength, their ease of use and the clinical significance of the additional data they give, which can't be caught through different advances being used in the clinical lab.