Biopsy acts as the elimination of small quantity of tissue or sample of cells that start from your body for the purpose examining under a microscope. All other diagnostic techniques can suggest whether cancer is existing in our body or not, but only a biopsy can give a definite diagnosis. The ejection of entire lump is called an excisional biopsy. A larger needle having a cutting tip is used to represent a column of tissue beyond a suspicious area is called core needle biopsy. In Vacuum-assisted biopsy, the suction device is gets operated to accumulate the sample which increases the fluid and cell quantity that is retrieved by using the needle. Endoscopic biopsy is most repeatedly used in gastric cancers to eliminate the tissues for examination. The process of eliminating small amount of solid tissue from a bone marrow handling with a needle is called bone marrow biopsy. This method is used to find whether the person is suffering with blood cancer or not. Blood cancers comprises of leukaemia, lymphoma, or multiple myeloma. The arrangement of an imaging procedure such as X-ray, computerized tomography (CT), magnetic resonance imaging (MRI) with a needle biopsy is known as Image-guided biopsy.